Figure 4. Eliciting maximal currents by hyperpolarisation or acidification.

A, example of the maximal conductance evoked by a saturating −200 mV squared voltage pulse followed by a tail current measured at 40 mV at pH_o 7.4. B, currents elicited in the same cell as in A by a pulse to −80 mV followed by a tail-current measuring pulse to 40 mV at pH_o 7.4 (grey trace) or pH_o 5.5. Notice that there was no difference in the instantaneous tail currents in A (1.36 nA) or in B at pH_o 5.5 (1.40 nA). C, summary of tail currents measured as in A and B (means ±s.e.m., n= 4).