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Protective effect of NAC on ATO-induced oxidative stress in HL-60 cells. Cells were incubated for 24 hr with 6 μg/mL ATO and various concentrations of NAC (25, 50, and 100 μM). Malondialdehyde formation was determined as described in Materials and Methods. *Significantly different from the control by ANOVA Dunnett's test; p < 0.05. **Significantly different from ATO alone by ANOVA Dunnett's test; p < 0.05. Data are representative of 3 independent experiments.
