. Author manuscript; available in PMC: 2010 May 1.

Published in final edited form as: J Biol Inorg Chem. 2009 Feb 6;14(4):573–585. doi: 10.1007/s00775-009-0471-2

Table 2.

Spin Hamiltonian parameters for the dominant axial and minor rhombic species obtained from the computer simulation of EPR spectra of Co(II)-loaded EcMetAP-I and PfMetAP-II in the presence of either A-310840 or A-311263

Wild-type enzymes	Axial			Rhombic
	g(x, y)	g(z)	E/D	g(x, y) [A(y) (10⁻³ cm⁻¹)]	g(z)	E/D
A-310840 binding to wild-type enzymes
[CoCo(PfMetAP-II)]	2.21	2.09	0.09	ND	ND	ND
[CoCo(EcMetAP-I)]	2.316	2.650	0.095	2.52 [8.6]	2.56	0.22
A-311263 binding to wild-type enzymes
[CoCo(PfMetAP-II)]	2.21	2.09	0.09	2.5−2.9 [10.6]	ND	ND
[CoCo(EcMetAP-I)]	2.316	2.650	0.095	ND	ND	ND

ND not determined