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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Immunol Rev. 2009 Mar;228(1):170–183. doi: 10.1111/j.1600-065X.2008.00751.x

Fig. 2. Multiple cell surface receptors promote Abl kinase activation and signaling.

Fig. 2

Abl kinases are activated by ligand-stimulated receptor tyrosine kinases (RTKs), adhesion receptors such as integrins and cadherins, and immunoreceptors such as the BCR and TCR. The activated Abl kinases signal to modulate cell proliferation, survival, or cytoskeletal processes in multiple cells types.