Table 1. Proteins identified in CA samples from the selected group of patients by liquid chromatography-electrospray ionization mass spectrometry.
Protein | Accession number | ‡Protein size (kDa) | Number of identified unique peptides (‡sequence coverage %) in following patients (P). | ||||||
P1 | P2 | P3 | P4 | P5 | P6 | P7 | |||
S100A8 | IPI00007047 | 10 | 2 (24) | 1 (11) | 1 (11) | 2 (24) | 2 (24) | 3 (31) | 3 (31) |
S100A9 | IPI00027462 | 13 | 3 (36) | 2 (25) | 1 (13) | 1 (13) | 1 (13) | 4 (31) | 3 (26) |
Human serum albumin | IPI00745872 | 67 | 10 (24) | 6 (14) | 24 (60) | 16 (38) | 13 (31) | # | 5 (10) |
α-1-acid glycoprotein 1 | IPI00022429 | 21 | # | 1 (8) | 2 (13) | 2 (24) | 1 (8) | # | # |
Zinc-α-2-glycoprotein | IPI00166729 | 32 | # | # | 3 (16) | 5 (21) | 3 (12) | # | # |
Hemoglobin subunit α | IPI00410714 | 15 | 2 (14) | # | 1 (11) | # | # | 1 (11) | # |
Hemoglobin subunit β | IPI00654755 | 16 | 1 (9) | # | # | # | # | # | # |
Cathepsin G | IPI00028064 | 27 | 2 (9) | # | # | # | # | 3 (11) | # |
Neutrophil defensin 1 | IPI00005721 | 8 | 1 (12) | # | # | # | # | # | # |
Myeloperoxidase | IPI00007244 | 79 | 1 (2) | # | # | # | # | 12 (10) | # |
Prostate-specific antigen | IPI00010858 | 27 | # | # | # | # | 1 (5) | # | # |
Haptoglobin | IPI00431645 | 31 | # | # | 5 (25) | # | # | # | # |
Calculated after removing signal peptide from their precursor sequence. # No significant identification.