Table 1.
A. Activity index | ||||||||
High | Moderate | Low | Remission | |||||
DAS28 original# | > 5,1 | < 5,1 | < 3,2 | < 2,6 | ||||
DAS28 modified cut off # | > 5,5 | < 5,5 | < 3,6 | < 2,4 | ||||
SDAI## | > 26 | < 26 | < 11 | < 3,3 | ||||
CDAI### | > 22 | < 22 | < 10 | < 2,8 | ||||
B. Response criteria | ||||||||
TJC | SJC | Patient global VAS | Patient pain VAS | Evaluator global | HAQ | ESR | CRP | |
ACR | yes | yes | yes/no | yes/no | yes/no | yes/no | yes/no | yes/no |
EULAR | yes | yes | yes | no | no | no | yes | no |
SDAI | yes | yes | yes | no | yes | no | no | yes |
CDAI | yes | yes | yes | no | yes | no | no | no |
# DAS28 = 0,56x√TJC28+0,28x√SJC28x0,7xlnESR+0,014xPat global VAS(in mm)
## SDAI=SJC+TJC+Pat global VAS(in cm)+Eval global VAS(in cm)+CRP(in mg/dL)
### CDAI = SJC+TJC+Pat global VAS(in cm)+Eval global VAS(in cm)
Cut points for activity states according to various indexes (Panel A) and components of response criteria (Panel B). Yes, required; no, not required; yes/no, in the ACR criteria, 3 of the variables marked "yes/no" are required (0 or 1 laboratory measure). TJC, tender joint count; SJC, swollen joint count; VAS, visual analogue scale; HAQ, health assessment questionnaire.