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. 2009 Apr 23;10:41. doi: 10.1186/1471-2474-10-41

Table 3.

Agreement between disease activity states at baseline and three month according to various indices, expressed as percentages and κ values.

Baseline
Valid N DAS28 modified cut off SDAI CDAI
1657 1657 1681

Reference criterion Valid N % κ % κ % κ

High disease activity
DAS28 original 1657 52/35 0,73 60/27 0,69 61/24 0,65
DAS28 modified cut off 1657 50/31 0,62 51/27 0,54
SDAI 1672 67/26 0,83
Moderate disease activity
DAS28 original 1657 29/55 0,66 23/61 0,63 20/62 0,58
DAS28 modified cut off 1657 25/52 0,52 21/53 0,42
SDAI 1672 24/69 0,80
Low disease activity
DAS28 original 1657 2.7/94 0,64 1.3/96 0,55 1.3/96 0,54
DAS28 modified cut off 1657 1.8/94 0,46 1.6/94 0,41
SDAI 1672 1.7/97 0,81
Remission
DAS28 original 1657 0.6/99 0,91 0.1/99 0,15 0.1/99 0,15
DAS28 modified cut off 1657 0.1/99 0,18 0.1/99 0,18
SDAI 1672 0/100 1,00

3 month

Valid N 1214 1224 1232
High disease activity
DAS28 original 1206 12/83 0,82 13/79 0,72 13/78 0.69
DAS28 modified cut off 1214 11/82 0,72 11/80 0.67
SDAI 1224 15/80 0,83
Moderate disease activity
DAS28 original 1206 34/50 0,67 32/46 0,55 30/45 0,49
DAS28 modified cut off 1214 29/50 0,56 26/49 0,47
SDAI 1224 35/55 0,79
Low disease activity
DAS28 original 1206 38/51 0,77 33/53 0,71 32/52 0,67
DAS28 modified cut off 1214 39/47 0,71 37/46 0,66
SDAI 1224 40/55 0,88
Remission
DAS28 original 1206 18/77 0,87 7.7/77 0,42 7.3/76 0,40
DAS28 modified cut off 1214 7.1/80 0,47 6.7/80 0,44
SDAI 1224 7.5/91 0,91

Percentages denote positive agreement/negative agreement, i.e. per cent patients achieving both compared activity states/per cent patients achieving neither.