Table 3.
Baseline | |||||||
Valid N | DAS28 modified cut off | SDAI | CDAI | ||||
1657 | 1657 | 1681 | |||||
Reference criterion | Valid N | % | κ | % | κ | % | κ |
High disease activity | |||||||
DAS28 original | 1657 | 52/35 | 0,73 | 60/27 | 0,69 | 61/24 | 0,65 |
DAS28 modified cut off | 1657 | 50/31 | 0,62 | 51/27 | 0,54 | ||
SDAI | 1672 | 67/26 | 0,83 | ||||
Moderate disease activity | |||||||
DAS28 original | 1657 | 29/55 | 0,66 | 23/61 | 0,63 | 20/62 | 0,58 |
DAS28 modified cut off | 1657 | 25/52 | 0,52 | 21/53 | 0,42 | ||
SDAI | 1672 | 24/69 | 0,80 | ||||
Low disease activity | |||||||
DAS28 original | 1657 | 2.7/94 | 0,64 | 1.3/96 | 0,55 | 1.3/96 | 0,54 |
DAS28 modified cut off | 1657 | 1.8/94 | 0,46 | 1.6/94 | 0,41 | ||
SDAI | 1672 | 1.7/97 | 0,81 | ||||
Remission | |||||||
DAS28 original | 1657 | 0.6/99 | 0,91 | 0.1/99 | 0,15 | 0.1/99 | 0,15 |
DAS28 modified cut off | 1657 | 0.1/99 | 0,18 | 0.1/99 | 0,18 | ||
SDAI | 1672 | 0/100 | 1,00 | ||||
3 month | |||||||
Valid N | 1214 | 1224 | 1232 | ||||
High disease activity | |||||||
DAS28 original | 1206 | 12/83 | 0,82 | 13/79 | 0,72 | 13/78 | 0.69 |
DAS28 modified cut off | 1214 | 11/82 | 0,72 | 11/80 | 0.67 | ||
SDAI | 1224 | 15/80 | 0,83 | ||||
Moderate disease activity | |||||||
DAS28 original | 1206 | 34/50 | 0,67 | 32/46 | 0,55 | 30/45 | 0,49 |
DAS28 modified cut off | 1214 | 29/50 | 0,56 | 26/49 | 0,47 | ||
SDAI | 1224 | 35/55 | 0,79 | ||||
Low disease activity | |||||||
DAS28 original | 1206 | 38/51 | 0,77 | 33/53 | 0,71 | 32/52 | 0,67 |
DAS28 modified cut off | 1214 | 39/47 | 0,71 | 37/46 | 0,66 | ||
SDAI | 1224 | 40/55 | 0,88 | ||||
Remission | |||||||
DAS28 original | 1206 | 18/77 | 0,87 | 7.7/77 | 0,42 | 7.3/76 | 0,40 |
DAS28 modified cut off | 1214 | 7.1/80 | 0,47 | 6.7/80 | 0,44 | ||
SDAI | 1224 | 7.5/91 | 0,91 |
Percentages denote positive agreement/negative agreement, i.e. per cent patients achieving both compared activity states/per cent patients achieving neither.