Table 1.
Leptin deficiency |
ob/ob mouse? (2) |
Human leptin deficiency? (40) |
Lipodystrophy |
SERBP-1 transgenic mouse? (35) |
A-ZIP/F-1 transgenic mouse? (36) |
aP2/DTA transgenic mouse? (37) |
Human lipodystrophy? (38) |
Leptin receptor defect |
db/db mouse? (2) |
Human OB-R defect? (40) |
ZDF (fa/fa) rat (10) |
Diet-induced obesity |
Rat and human? |
? indicates that careful measurements of fat in nonadipocytes have not been reported but are predicted to be high.