Table 1.
Population | Gene | No. of haplotypes | Haplotype diversity |
Tajima's D |
Fu and Li's D* |
Fu and Li's F* |
Fu's Fs |
|||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Estimate | Variance | Value | P | Value | P | Value | P | Value | P | |||
Indian (this study) | CAMP | 8 | 0.108 | 0.0005 | −1.79 | < 0.05 | −2.91 | < 0.05 | −3.02 | < 0.02 | −12.28 | < 0.05 |
DEFA4 | 31 | 0.816 | 0.0001 | −0.07 | > 0.10 | −1.01 | > 0.10 | −0.75 | > 0.10 | −7.40 | < 0.05 | |
DEFA5 | 21 | 0.699 | 0.0004 | −1.26 | > 0.10 | −1.16 | > 0.10 | −1.45 | > 0.10 | −10.27 | < 0.05 | |
DEFA6 | 37 | 0.902 | 0.0001 | −0.10 | > 0.10 | −0.92 | > 0.10 | −0.71 | > 0.10 | −16.88 | < 0.05 | |
DEFB1 | 106 | 0.922 | 0.0001 | 0.00 | > 0.10 | −1.53 | > 0.10 | −0.90 | > 0.10 | −22.54 | < 0.05 | |
MBL2 | 46 | 0.879 | 0.0001 | 0.40 | > 0.10 | −2.12 | 0.05 < P < 0.10 | −1.13 | > 0.10 | −2.74 | > 0.10 | |
TLR1 | 45 | 0.757 | 0.0007 | −0.37 | > 0.10 | −1.67 | > 0.10 | −1.29 | > 0.10 | −4.87 | > 0.10 | |
TLR2 | 34 | 0.659 | 0.0007 | −1.24 | > 0.10 | −2.46 | < 0.05 | −2.35 | < 0.05 | −22.34 | < 0.05 | |
TLR4 | 58 | 0.78 | 0.0005 | −1.23 | > 0.10 | −3.50 | < 0.02 | −2.98 | < 0.02 | −34.49 | < 0.05 | |
TLR5 | 35 | 0.848 | 0.0001 | 0.64 | > 0.10 | −0.77 | > 0.10 | −0.16 | > 0.10 | −1.07 | > 0.10 | |
TLR6 | 34 | 0.833 | 0.0002 | 0.47 | > 0.10 | −0.30 | > 0.10 | 0.07 | > 0.10 | 1.10 | > 0.10 | |
TLR9 | 30 | 0.719 | 0.0004 | −1.28 | > 0.10 | −2.66 | < 0.05 | −2.51 | < 0.05 | −15.55 | < 0.05 | |
European-American | DEFB1 | 17 | 0.875 | 0.0012 | 1.58 | > 0.10 | 0.98 | > 0.10 | 1.43 | > 0.10 | 9.48 | > 0.10 |
TLR1 | 11 | 0.724 | 0.0027 | −0.50 | > 0.10 | 1.20 | > 0.10 | 0.71 | > 0.10 | 2.60 | > 0.10 | |
TLR2 | 10 | 0.774 | 0.0021 | −0.44 | > 0.10 | −1.37 | > 0.10 | −1.26 | > 0.10 | −1.85 | > 0.10 | |
TLR4 | 16 | 0.875 | 0.0009 | −0.26 | > 0.10 | 0.53 | > 0.10 | 0.30 | > 0.10 | −0.17 | > 0.10 | |
TLR5 | 22 | 0.949 | 0.0002 | 0.60 | > 0.10 | 1.00 | > 0.10 | 1.02 | > 0.10 | 0.90 | > 0.10 | |
TLR6 | 12 | 0.756 | 0.0026 | 1.58 | > 0.10 | 1.12 | > 0.10 | 1.52 | 0.05 < P < 0.10 | 2.66 | > 0.10 | |
TLR9 | 11 | 0.762 | 0.0015 | −0.64 | > 0.10 | −2.23 | 0.05 < P < 0.10 | −2.01 | 0.05 < P < 0.10 | −2.65 | > 0.10 | |
African-American | DEFB1 | 23 | 0.949 | 0.0004 | −0.28 | > 0.10 | 0.38 | > 0.10 | 0.17 | > 0.10 | 1.45 | > 0.10 |
TLR1 | 14 | 0.878 | 0.0024 | −1.28 | > 0.10 | −2.14 | 0.05 < P < 0.10 | −2.20 | 0.05 < P < 0.10 | −1.55 | > 0.10 | |
TLR2 | 18 | 0.917 | 0.0003 | −0.96 | > 0.10 | −2.32 | 0.05 < P < 0.10 | −2.20 | 0.05 < P < 0.10 | −8.16 | > 0.10 | |
TLR4 | 30 | 0.969 | 0.0002 | −0.68 | > 0.10 | −0.37 | > 0.10 | −0.57 | > 0.10 | −6.31 | > 0.10 | |
TLR5 | 28 | 0.946 | 0.0006 | −0.78 | > 0.10 | −1.35 | > 0.10 | −1.36 | > 0.10 | −0.77 | > 0.10 | |
TLR6 | 18 | 0.925 | 0.0003 | −0.22 | > 0.10 | 0.21 | > 0.10 | 0.07 | > 0.10 | −0.12 | > 0.10 | |
TLR9 | 11 | 0.755 | 0.0025 | −0.22 | > 0.10 | −0.13 | > 0.10 | −0.19 | > 0.10 | −1.84 | > 0.10 |