Table 3.
Brain volumetric and perfusion measurements of the 2 study groups
| APOE ε4-noncarriers | APOE ε4-carriers | P | |
|---|---|---|---|
| Brain volumetry | |||
| Whole brain volume, mL | 1487.5 (± 159.3) | 1515.8 (± 122.2) | 0.55 |
| Gray matter* | 47.1 (± 1.7) | 47.2 (± 1.4) | 0.86 |
| White matter* | 33.4 (± 0.9) | 33.3 (± 1.5) | 0.74 |
| Cerebrospinal fluid* | 19.4 (± 1.9) | 19.5 (± 1.4) | 0.93 |
| Left hippocampus* | 0.27 (± 0.02) | 0.26 (± 0.03) | 0.15 |
| Right hippocampus* | 0.31 (± 0.02) | 0.29 (± 0.04) | 0.11 |
| Brain perfusion values, units of mL·100 g·min | |||
| Whole brain | 21.4 (± 3.9) | 22.5 (± 5.7) | 0.50 |
| Frontal lobe | 18.6 (± 3.8) | 19.6 (± 4.4) | 0.49 |
| Parietal lobe | 28.0 (± 5.8) | 29.3 (± 7.9) | 0.57 |
| Temporal lobe | 24.1 (± 4.6) | 25.3 (± 6.6) | 0.54 |
| Occipital lobe | 23.9 (± 5.8) | 25.5 (± 7.4) | 0.48 |
| Left hippocampus | 31.1 (± 7.6) | 30.9 (± 8.9) | 0.95 |
| Right hippocampus | 31.1 (± 7.2) | 32.9 (± 9.5) | 0.51 |
Values denote mean (± SD). *, Values are expressed as percentage of whole-brain volume.