Table 1.

Serum hyaluronate and hepatocyte enzymes

	Hyaluronate, ng/ml	AST, units/ml	ALT, units/ml
Intact	<10	13  ±  5	8  ±  3
DMN-saline	430  ±  61	7,652  ±  1,695	4,211  ±  1,010
DMN-AdLacZ	411  ±  46	8,078  ±  1,515	4,041  ±  768
DMN AdTβ-TR	22  ±  4	78  ±  6	67  ±  7

Serum hyaluronate and hepatocyte enzymes in intact and DMN-treated rats. Rats were treated as described in the legend to Fig. 1. Blood was collected 3 weeks after gene transfer and DMN treatment. Hyaluronate, AST, and ALT are shown as mean ± SE (n = 7). Intact rats were also analyzed as controls.