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(A) Tophi infiltration was noted between flexor digitorum profundus tenosynovium and carpal bones on MRI (white arrow, tophi infiltration). (B) Urate crystal and lymphocyte infiltration show chronic tophaceous arthritis (H-E stain, ×200). (C) When examined with a polarizing filter, they are yellow when aligned parallel to the axis of the red compensator, but they turn blue when aligned across the direction of polarization (ie, they exhibit negative birefringence).
