Table 2.
Publications reporting the outcome with computer screening systems for Pap tests
| Reference | Date | Screening system primary/interactive | Major finding |
|---|---|---|---|
| [32] | 1995 | Primary (AutoPap®) | Superior false negative detection to random rescreening |
| [39] | 1999 | Primary (AutoPap®) | HSIL placed in top three quintiles |
| [44] | 2001 | Primary (AutoPap®) | High sensitivity for review classification of LSIL+ |
| [45] | 2002 | Primary (AutoPap®) | All cases of HSIL+ placed in top two ranking quintiles |
| [46] | 2004 | Primary (BD FocalPoint Slide Profiler®) | High % of HSIL placed in top two ranking quintiles |
| [47] | 2005 | Interactive (ThinPrep® Imaging System) | Increased sensitivity for SIL detection |
| [48] | 2006 | Interactive (ThinPrep® Imaging System) | Increased sensitivity for SIL detection, with biopsy confirmation of increased HSIL detection |
| [49] | 2007 | Interactive (BD FocalPoint GS®) | High sensitivity for SIL detection |
| [50] | 2007 | Interactive (ThinPrep® Imaging System) | Increased sensitivity for SIL detection |
| [41] | 2007 | Interactive (ThinPrep® Imaging System) | Increased sensitivity for SIL detection, with reduction of false negative rate; increase in cytotechnologist job satisfaction |
| [43] | 2007 | Interactive (ThinPrep® Imaging System) | Increased productivity |
| [40] | 2007 | Interactive (ThinPrep® Imaging System) | Increased sensitivity for SIL detection |
| [42] | 2007 | Interactive (ThinPrep® Imaging System) | Increased productivity |
| [51] | 2008 | Interactive (ThinPrep® Imaging System) | Unchanged ASCUS and HPV DNA positive rates |
ASCUS = atypical squamous cells of undetermined significance, SIL = squamous intraepithelial lesion, LSIL = low grade SIL, HSIL = high grade SIL, + = higher diagnostic category