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. 2009 Mar 26;8:5. doi: 10.4103/1477-3163.49014

Figure 12.

Figure 12

Colonic tumors developed in mice that received AOM and DSS. (a) Macroscopic view shows a number of colonic tumors in the distal colons. (b–e) Histopathology findings of colonic lesions induced by AOM and DSS. Some colonic adenocarcinomas invade the serosa (b). Most adenocarcinomas are of the well-differentiated type, but some moderately differentiated (b) and poorly differentiated types are also observed. Dysplastic crypts (d) are frequently observed in the mucosa, which develop many small adenomas (e)