Table 1.
Description of protein set | Number of proteins in the set | Macroscopic crystals after methylation | Diffraction-quality crystals after methylation | Structures solved | Overall success rate (percentage of structures solved) |
---|---|---|---|---|---|
Crystallized previously but crystals unsuitable for structure determination | 269 | 59 | 33 | 20 | 7.4 |
Screened previously but no crystals obtained | 85 | 8 | 5 | 5 | 5.9 |
Proteins not previously screened | 16 | 5 | 2 | 1 | 6.3 |
Total | 370 | 72 | 40 | 26 | 7.0 |