Table 2.

Effect of GnRH analogues and P-X-GnRH-III on proliferation of human tumor cell lines

Cell line	Cells, % of control
	GnRH-III	Buserelin	P-X-GnRH-III
MCF-7	68  ±  5	87  ±  2	23  ±  7
MDA-MB-231	64  ±  6	80  ±  4	21  ±  6
PC3	82  ±  3	NT	66  ±  5
Ishikawa	79  ±  4	NT	52  ±  5

Cells were treated with 50 μM conjugated peptide or free peptide at the beginning only with P-X-GnRH-III, or at the beginning and on alternate days of incubation with the free peptides for 5 days. Cell numbers are expressed as percentage of cell numbers in control cultures. NT, not tested.