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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Arthritis Rheum. 2008 Dec;58(12):3884–3891. doi: 10.1002/art.24026

Figure 1. α8 integrin is expressed in glomeruli of normal and nephritic mice.

Figure 1

Representative photomicrographs showing indirect immunofluorescence staining of sections from paraformaldehyde fixed kidneys of 3 (A), 6 (B) and 9 (C) month old (NZM/NOD) F1 female mice stained with a rabbit anti-α8 integrin antibody. Glomeruli show expression of α8 integrin (arrows) at all ages. Some interstitial cells (arrowheads) are also positive for α8 integrin expression. Section stained with rabbit IgG was used as negative control (D). Bottom panel (E-G) shows H&E stained sections of formalin fixed kidneys from the same mice showing normal glomerulus (E), early acute GN (F) and chronic GN (G).