Figure 5.

Activation of εPKC increases the activity of mitochondrial respiratory chain complexes I, III, and IV in synaptosomes isolated from hippocampus of ischemic preconditioned rats. Hippocampal synaptosomes were isolated at 48 h of reperfusion from sham (n = 6) or IPC (n = 6)-treated animals. Complex I, II, III, and IV activities in synaptosomes treated with tat or ψεRACK in both experimental groups. The results are expressed as mean ± SEM of percentage of oxygen consumption in tat-treated group. *p < 0.05, ψεRACK versus tat-treated synaptosomes.