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. 2009 Mar 13;18(11):2078–2090. doi: 10.1093/hmg/ddp120

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©2009 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Module identification. (A) Number of significant modules (size <50 and score >3) identified by Jactive modules in MS and in a panel of other autoimmune (RA, T1D and CD), other neurological (AD and BD), and other unrelated (T2D, HT and CAD) diseases. Each disease is represented by a different color. Filled bars correspond to the results obtained when real P-values were used to search for modules. Open bars are the results obtained with randomized P-values. (B) Scores of the top 20 modules obtained with real (solid symbols) or randomized (open symbols) P-values for each disease. The average and standard deviation of 10 randomizations is shown for each disease.