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PPARα genotype distribution of study population
| Whole population (n=928) |
Caucasians (n=602) |
African-Americans (n=326) |
p-value1 | ||||
|---|---|---|---|---|---|---|---|
| L162V (rs1800206) |
CC | 850 | CC | 534 | CC | 316 | <0.001 |
| GC | 72 | GC | 62 | GC | 10 | ||
| GG | 6 | GG | 6 | GG | 0 | ||
|
Whole population (n=911) |
Caucasians (n=590) |
African-Americans (n=321) |
|||||
| Intronic SNP (rs4253728) |
GG | 588 | GG | 309 | GG | 279 | <0.001 |
| GA | 278 | GA | 240 | GA | 38 | ||
| AA | 45 | AA | 41 | AA | 4 | ||
comparison of minor allele frequency between Caucasians and African-Americans using chi-squared test
