Table 2.

Main function groups of oncogene domains.

Go annotation	Domain
ATP binding	Pkinase, DEAD, Helicase_C, Pkinase_C, MutS_V, MutS_IV, MutS_III MutS_II MutS_I Furin-like, Ephrin_lbd
protein binding	zf-C3HC4, Death, LRR_1, PDZ, SAMP, EB1_binding, APC_basic, APC_15aa
DNA/RNA binding	Myb_DNA-binding, P53, bZIP_Maf, bZIP_2, RRM_1, zf-C2H2, zf-C4, bZIP_1, Ets, SAM_PNT
signal transduction	Cbl_N, wnt, C1_1, Death, RhoGAP, Ras
growth factor receptor activity	FGF, PDGF, PDGF_N, IGFBP
protein tyrosine kinase activity	Pkinase, Pkinase_Tyr, SH2, SH3, ig, I-sev, V-set
regulation of transcription	HLH, RHD, Wos2, Hormone_recep, zf-C4, bZIP_1, Ets, IRF, p53, Myc_N, WT1, E2F_TDP, Myc-LZ, bZIP_Maf, bZIP_2
regulation of apoptosis	BH, BH4
receptor factor activity/binding	Recep_L_domain, NCD3G, 7tm_1, 7tm_3, PSI
Wnt receptor signalling pathway	Wnt
zinc ion binding	zf-C2H2, zf-C3HC4, zf-C4, zf-RanBP
calcium ion binding	Cadherin, Cadherin_C
transcription factor activity	Hormone_recep, zf-C4, bZIP_1, Ets, RHD, IRF, P53, Myc_N, E2F_TDP, Myc-LZ