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. Author manuscript; available in PMC: 2009 May 7.
Published in final edited form as: J Neuroendocrinol. 2008 Dec 6;21(2):141–150. doi: 10.1111/j.1365-2826.2008.01814.x

Figure 1.

Figure 1

Oestrogen and STX significantly attenuate the body weight gain in female guinea pigs after ovariectomy. Female guinea pigs were ovariectomised and allowed to recover for 1 week (day 0) before being given bi-daily subcutaneous injections of propylene glycol (vehicle), oestradiol benzoate (EB; 8 μg/kg, triangles), or STX (6 mg/kg, squares). A two-way ANOVA (repeated measures) revealed an overall significant effect of both EB and STX (p < 0.001), and post hoc NewmañKeuls analysis revealed daily significant differences between STX and vehicle-treated groups (*p < 0.5; ** p < 0.01). Symbols represent the mean ± SEM of five, five and seven animals per group for vehicle, EB and STX treatment, respectively. Modified from Roepke et al., 2008, Endocrinology online.