Table 3.
Summary of results concerning circadian genes
| C57BL/6J | C57.YA | Interaction | ||||
| Gene Symbol | Gene Name | FC | FDR | FC | FDR | FDR |
| Arntl | aryl hydrocarbon receptor nuclear translocator-like | -1.10 | 0.531 | -5.30 | 0.000 | 0.006 |
| Dbp | D site albumin promoter binding protein | -1.05 | 0.772 | 2.94 | 0.000 | 0.006 |
| Tef | thyrotroph embryonic factor | 1.02 | 0.851 | 2.16 | 0.001 | 0.008 |
| Per2 | period homolog 2 (Drosophila) | 1.11 | 0.531 | 2.95 | 0.001 | 0.009 |
| Cry2 | cryptochrome 2 (photolyase-like) | -1.08 | 0.370 | 1.42 | 0.001 | 0.019 |
| Clock | circadian locomoter output cycles kaput | -1.10 | 0.284 | -1.62 | 0.001 | 0.024 |
| Nr1d2 | nuclear receptor subfamily 1, group D, member 2 | 1.08 | 0.561 | 1.84 | 0.001 | 0.033 |
| Per3 | period homolog 3 (Drosophila) | 1.08 | 0.503 | 1.67 | 0.001 | 0.034 |
| Rora | RAR-related orphan receptor alpha | 1.02 | 0.845 | 1.46 | 0.002 | 0.081 |
| Per1 | period homolog 1 (Drosophila) | -1.01 | 0.923 | 1.92 | 0.004 | 0.087 |
| Csnk1e | casein kinase 1, epsilon | 1.02 | 0.826 | 1.23 | 0.016 | 0.230 |
| Csnk1d | casein kinase 1, delta | 1.04 | 0.789 | 1.23 | 0.061 | 0.437 |
| Nr1d1 | nuclear receptor subfamily 1, group D, member 1 | -1.36 | 0.017 | -1.39 | 0.006 | 0.920 |
| Bhlhb2 | basic helix-loop-helix domain containing, class B2 | 1.14 | 0.251 | 1.15 | 0.135 | 0.942 |
Genes were considered as "circadian" on the basis of information from both the KEGG pathway database and additional annotation from the literature. FC: fold change of CX over Sham operated animals; FDR: P-values for the interaction between strain and treatment effects after adjustment for multiple comparisons with an FDR transformation (see methods); FDR values < 0.1 are formatted in bold.