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. 2009 Mar 30;10:16. doi: 10.1186/1471-2156-10-16

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Copyright © 2009 Brooks et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Discrimination between IBD loci and loci with no sharing as a function of overall process efficiency. The Discrimination Factor (DF) is the ratio of a value measured when the signal is derived from pairs when the fragments are enriched for IBD sharing to the value for pairs with no sharing. The overall process efficiency indicates the extent that the process has eliminated homohybrids and non-identical heterohybrids. Plots of DF as a function of the efficiency (see Equation 1) are shown for biparental sharing (IBD-2, gray) and monoparental sharing (IBD-1, black). The ratio of the DFs for IBD-2 versus IBD-1 is also shown (dashed).