Table 1.

Baseline characteristics of the subjects recruited into each study protocol

	Dose–response	Tolerance	Mechanistic
Number	6	8	8
Sex (M/F)	6/0	8/0	8/0
Age (years)	31.2 (1.3)	34.4 (5.2)	34.4 (4.5)
BMI (kg m–2)	25.8 (0.8)	25.7 (1.1)	25.7 (1.0)
Baseline systolic BP	140 (12)	141 (14)	134 (14)
Baseline diastolic BP	64 (8)	68 (7)	68 (11)
Baseline heart rate	56 (8)	61 (16)	62 (7)
Baseline FBF ratio	1.0 (0.1)	1.2 (0.1)	1.2 (0.0)

Results are presented as mean ± SD. BMI, body mass index; BP, blood pressure; FBF, forearm blood flow.