Table 3.
Quantification of midazolam N-glucuronide (MDZG) eliminated in the urine of six individuals over 24 h following 3 mg oral and 1 mg i.v. midazolam
Subject | Amount of MDZG eliminated in urine over 24 h (µg) 3-mg oral dose | 1-mg i.v. dose |
---|---|---|
3 | 56.3 | 40.7 |
4 | 21.0 | 20.8 |
5 | 148.2 | 59.8 |
6 | 59.2 | 17.6 |
10 | 37.1 | 26.5 |
11 | 35.3 | 35.1 |
Geometric mean | 48.8 | 26.5 |
SEM | 13.2 | 5.7 |