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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: J Cell Physiol. 2008 Aug;216(2):419–425. doi: 10.1002/jcp.21408

Figure 6. Cytochrome c release following an apoptogen challenge.

Figure 6

siUCP3 and pSHH (control) cells were challenged with 100 nM staurosporine for 6 h. Cytoplasmic and mitochondrial fractions were collected and subjected to Western blot analysis for cytochrome c localization. Note, the apoptogen caused release of cytochrome c from mitochondria to the cytosol in control cells. Also note the predominant localization of cytochrome c in the cytosolic fraction of the silenced chondrocytes, even in the absence of staurosporine.