Table 1. Characteristics of 15,280 African American adults by study population.
| Diabetes status | ||||||||||
| Study | No. of samples | DNA source | Phase of marker panel | Female, % | Age (yrs) | European ancestry from autosomes, % | European ancestry from the X chromosome, % | BMI (Kg/m2) | No. with information on diabetes status | Diabetes, % |
| ARIC | 3,522 | genomic | 3 | 62.1 | 53.5±5.8 | 17.6±10.2 | 14.2±7.4 | 29.6±6.2a | 3,450 | 19.5 |
| BCFRb | 268 | genomic | 2 | 100.0 | 50.3±9.4 | 22.7±12.4 | 17.9±9.2 | 30.3±6.7a | 0 | - |
| CAREb | 365 | WGA | 3 | 100.0 | 48.9±8.0 | 22.0±11.5 | 17.3±8.4 | 27.7±6.1 | 0 | - |
| DHS | 1,718 | genomic | 1 | 57.5 | 44.8±10.2 | 16.2±8.2 | 13.1±6.1 | 31.5±8.2a | 1,718 | 13.6 |
| FINDb | 1,445 | genomic | 3 | 50.4 | 48.4±12.4 | 17.1±8.4 | 13.9±6.1 | 28.8±7.2 | 1,445 | 22.0 |
| GCIb | 503 | genomic | 2 | 54.5 | 57.9±13.6 | 15.3±11.2 | 12.6±8.2 | 31.6±7.0 | 503 | 8.9 |
| Health ABC | 1,172 | WGA | 2 | 57.1 | 73.4±2.9 | 20.9±12.8 | 16.7±9.4 | 28.5±5.2a | 1,164 | 21.4 |
| JHS | 2,141 | genomic | 2/3 | 60.0 | 52.4±11.1 | 17.9±9.2 | 14.5±6.7 | 31.9±7.1a | 2,106 | 17.9 |
| LIFEb | 108 | WGA | 3 | 100.0 | 42.2±5.3 | 21.3±11.0 | 17.1±7.9 | 29.0±6.9 | 0 | - |
| MECb | 3,199 | genomic | 1/2/3 | 31.3 | 62.7±8.1 | 23.4±14.0 | 18.4±10.1 | 28.3±5.3 | 1,551 | 58.9 |
| MrOS | 199 | WGA | 3 | 0.0 | 71.7±5.2 | 21.2±13.6 | 16.9±9.9 | 28.5±4.4a | 182 | 27.5 |
| SFBABCSb | 152 | genomic | 2 | 100.0 | 55.1±11.8 | 22.6±14.7 | 17.9±11.0 | 30.5±6.0a | 0 | - |
| SOF | 368 | WGA | 3 | 100.0 | 75.0±4.7 | 24.4±13.8 | 19.1±10.1 | 29.9±5.8a | 368 | 16.3 |
| WCHSb | 120 | genomic | 2 | 100.0 | 50.1±9.3 | 16.7±14.8 | 13.6±11.2 | 30.3±6.5a | 0 | - |
| Total | 15,280 | - | - | 55.7 | 56.0±12.2 | 19.3±11.5 | 15.5±8.4 | 29.8±6.6 | 12,487 | 23.4 |
Ranges are given in terms of ±1 standard deviation. ARIC, Atherosclerosis Risk in Communities Study; BCFR, Breast Cancer Family Registry; CARE, Los Angeles component of the Women's Contraceptive and Reproductive Experiences Study, DHS, Dallas Heart Study; FIND, Family Investigation of Nephropathy and Diabetes Study; GCI, Genomics Collaborative Study; Health ABC, Health, Aging and Body Composition Study; JHS, Jackson Heart Study; LIFE, Learning the Influence of Family and the Environment Study; MEC, Multiethnic Cohort of Los Angeles and Hawaii; MrOS, Osteoporotic Fractures in Men Study; SFBABCS, the San Francisco Bay Area Breast Cancer Study; SOF, Study of Osteoporotic Fractures; WCHS, Women's Circle of Health Study; WGA, whole genome amplification.
BMI were measured in an actual clinical visit in the six prospective cohort studies and in the BCFR, SFBABCS and WCHS; for others, BMI was calculated from self-reported weight and height.
These studies include case-control studies and so are not a representative cross-section of the populations. BCFR, CARE, LIFE, SFBABCS and WCHS oversampled women with breast cancer. FIND oversampled individuals with nephropathy. GCI focused on individuals with hypertension. MEC oversampled individuals with type 2 diabetes, prostate cancer, breast cancer, and hypertension.