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Pulmonary targeting of b-125I-anti-PECAM/SA in vivo. (A) Rats were injected via tail vein with 125I-b-IgG (filled bars) or 125I-b-anti-PECAM (open bars) either conjugated with streptavidin (+) or without streptavidin (−). (B) Rats were injected with b-125I-anti-PECAM/SA via the tail vein (filled bars) or via the left ventricle (open bars). One hour after injection, rats were sacrificed, and 125I in the tissues was determined (mean ± SD, n = 5).
