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. Author manuscript; available in PMC: 2009 May 8.
Published in final edited form as: J Allergy Clin Immunol. 2007 Oct 24;120(6):1441–1448. doi: 10.1016/j.jaci.2007.08.012

TABLE II.

Predictive values of individual and combined phospho-STAT1 and phospho-STAT6 levels for subject group identification in comparison with plasma IL-4 and IgE levels

Groups to identify Proposed predictor P value
(log likelihood)		 Area under
the ROC curve
Asthmatic patients (all) vs healthy control subjects Phospho-STAT1 <10−4 0.95
Phospho-STAT6 <10−4 0.89
Phospho-STAT1 × Phospho-STAT6 <10−4 0.96
AA (all) vs NA (all) Phospho-STAT1 .001 0.91
Phospho-STAT6 .024 0.69
Phospho-STAT1 × Phospho-STAT6 .015 0.91
Plasma IgE <10−4 1.00
Plasma IL-4 .021 0.80
Asthmatic patients not taking OCSs vs asthmatic Phospho-STAT1 .77 0.61
   patients taking OCSs Phospho-STAT6 .005 0.82
Phospho-STAT1 × Phospho-STAT6 <10−4 1.00
Plasma IgE .015 0.82
Plasma IL-4 .013 0.65

See DeLong et al.33

AA, Allergic asthmatic patients; NA, nonallergic asthmatic patients.