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. 2008 Aug 31;40(4):407–417. doi: 10.3858/emm.2008.40.4.407

Figure 5.

Figure 5

BC excreted from macrophages regulates the expressional level of apoE, CYP7A1 and CYP7B1 in an FXR-dependent manner in HepG2 cells. The HepG2 cells (5 × 106) were incubated with 50% TMCM, derived from Figure 4, and 50% DMEM containing 10% LPDS with or without the indicated concentration of GS for 48 h. Each level of protein expression was analyzed by Western blot. The intensity of the detected bands is demonstrated as an average of three independent experiments. #,*,†P < 0.01 versus the indicated control.