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. 2008 Feb 20;40(1):109–117. doi: 10.3858/emm.2008.40.1.109

Figure 5.

Figure 5

Stability of MDR1 mRNA in control and mtDNA-depleted HCT-8 cells. (A) Control and mtDNA-depleted HCT-8 cells were treated with 12.5 µg/ml actinomycin D for various times, followed by extraction and analysis of RNA via RT-PCR. GAPDH is used as an internal control. A representative result of three independent experiments is shown. (B) The level of MDR1 transcript was analyzed by real-time PCR. The level of MDR1 mRNA was expressed as a percentage relative to that observed at time 0. The Results are expressed as the means ± SD of three independent experiments.