TABLE 2.

Epitope mapping of mAbs reactive with mouse ANGPTL3 A series of mAbs were tested for their reactivity with overlapping peptides corresponding to mouse ANGPTL3 amino acids Ser¹⁷–Met¹¹⁶. A “–” sign indicates no immunoreactivity and “+” sign indicates positive immunoreactivity. The column heading “ANGPTL3” corresponds to N′-mANGPTL3 (Ser¹⁷–Arg²²¹; accession NP_038941.1).

mAb	ANGPTL3 peptide
	Ser17–Gly66	Asp42–Glu91	Gln67–Met116	ANGPTL3
3E11	–	+	+	+
21H9	–	+	+	+
6C6	–	+	–	+
34B2	–	+	+	+
8E2	–	+	+	+
30H2	–	–	+	+
1.251.1	–	+	–	+
1.173.1	–	+	–	+
1.135.1	–	+	–	+
1.424.1	–	+	–	+
1.431.1	–	+	–	+
5.50.3	+	–	–	+
1.431.1	–	+	–	+