Table 2.
Comparison of foci of shock and inflammation between the human SIDS cases and neonatal rats
SIDS infants | Neonatal rats | |
---|---|---|
Heart | Sparse hypereosinophilic myocytes with condensed and shrunken nuclei | Sparse hypereosinophilic myocytes with condensed and shrunken nuclei |
Subendocardial hemorrhages | ||
Liver | Marbled appearance | Marbled appearance |
Fibrin thrombi in capillaries | Areas of hemorrhage and necrosis | |
Increased infiltration of PMNs | ||
Increased megakaryocytes | ||
Circulation | Recruitment of inflammatory cells | Recruitment of inflammatory cells |
Megakaryocytes in circulation | Increased megakaryocytes | |
PMNs in the circulation | Margination of PMNs along vessel walls | |
Fibrin thrombi in the capillaries: DIVC | ||
Kidney | Pale | Pale |
Tubular cell necrosis | Tubule degeneration | |
Glomeruli retractions and exudation within the glomerular capsule |
PMNs, polymorphonuclear leukocytes; DIVC, disseminated intravascular coagulation.