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. 2008 Dec 5;117(4):587–596. doi: 10.1289/ehp.0800251

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Effects of 30 μM chlorpyrifos (A), diazinon (B), dieldrin (C), and Ni²⁺ (D) exposure on expression of antioxidant genes in differentiating PC12 cells. The vertical lines separate genes encoding catalase and the superoxide dismutase isoforms from those involved in glutathione synthesis and redox status.

*Significant main treatment effect. ^†Treatment × time interaction and times for which treatment effects were present. Multivariate ANOVA (all treatments, all genes, time) indicates a significant main effect of treatment (p < 0.02) and interactions of treatment × gene ( p < 0.0001) and treatment × gene × time (p < 0.006).