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. 2008 Sep 24;28(39):9670–9681. doi: 10.1523/JNEUROSCI.2151-08.2008

Figure 1.

Figure 1.

A, B, Light micrographs showing retrogradely labeled neurons in VTA. After injection of the retrograde tracer, FG, into the mPFC (inset, A), peroxidase-labeled neurons are mainly located within the parabrachial subdivision of the VTA (dotted circle in A). After FG injection to the NAc (inset, B), retrogradely labeled neurons are located within the paranigral VTA (dotted circle in B). C, D, Light micrographs of plastic embedded TH and GluR1 labeled tissue. Both the PB and PN regions of the VTA show peroxidase labeling for TH, whereas the GluR1-gold is not discernable at this magnification (C). A higher magnification (D) includes trapezoids demarcating the areas used for electron microscopic analysis of the PB and PN VTA. CPu, Caudate–putamen; fmcc, foceps minor corpus callosum; mp, mammilary peduncle; PAG, periaqueductal gray; SC, somatosensory cortex; SNc, substantia nigra zona compacta; SNr, substantia nigra zona reticulate; d, dorsal; l, lateral. Scale bars, 500 μm.