Table 4.

List of top ten significant reporter metabolite and subsystem scores for the gdh1/GDH2 vs. wild type comparison in anaerobic conditions.

Reporter metabolite	Z-score	No of reactions
Glutamate [c]	4.52	35
Aspartate [c]	3.21	11
Alpha-ketoglutarate [c]	2.66	17
Glycine [c]	2.65	7
Pyruvate [m]	2.56	7
Ribulose-5-phosphate [c]	2.43	4
Threonine [c]	2.28	6
10-formyltetrahydrofolate [c]	2.27	5
Fumarate [c]	2.27	5
L-proline [c]	2.04	4
Reporter subsystem	Z-score	No of reactions
Valine, Leucine, and Isoleucine Metabolism	3.97	15
Tyrosine, Tryptophan, and Phenylalanine Metabolism	3.39	23
Pentose Phosphate Pathway	3.29	11
Purine and Pyrimidine Biosynthesis	3.08	40
Arginine and Proline Metabolism	2.96	19
Threonine and Lysine Metabolism	2.74	14
NAD Biosynthesis	2.66	7
Alanine and Aspartate Metabolism	2.65	6
Histidine Metabolism	2.24	10
Cysteine Metabolism	1.85	10