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. 2009 Apr 16;8:7. doi: 10.1186/1475-925X-8-7

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Copyright © 2009 Behrens et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Modified bone adaptation law. In this figure the bone adaptation law of Huiskes with the conducted modifications is shown. Here, the correlation between the ABD evolution rate and the bone remodelling stimulus is presented. Huiskes et al. supposed that the bone adaptation rate and the bone modelling stimulus ξ correlated linearly with each other [18]. Furthermore, they used the dead zone z, in which changes in the physiological load situation do not cause remodelling processes. In the modified law, we introduced a limitation of the bone formation and assumed that severe overloading causes a necrosis in the bone structure and thus bone resorption.

Inline graphic — Modified bone adaptation law. In this figure the bone adaptation law of Huiskes with the conducted modifications is shown. Here, the correlation between the ABD evolution rate and the bone remodelling stimulus is presented. Huiskes et al. supposed that the bone adaptation rate and the bone modelling stimulus ξ correlated linearly with each other [18]. Furthermore, they used the dead zone z, in which changes in the physiological load situation do not cause remodelling processes. In the modified law, we introduced a limitation of the bone formation and assumed that severe overloading causes a necrosis in the bone structure and thus bone resorption.