Table 1.

Reported incidences of peptic ulcer complications (cases per 100000 inhabitants per year).

Country (ref)	Period	Reported incidences		Comment	Studied variable
		perforation	Bleeding
Norway (18)	1935–1990	About 10		Report birth cohort specific risks for perforation	Admittance rates
USA (44)	1956–1985	10-5	7-4	Relatively stable incidence of emergency operations for PUC	Emergency operations
England and Wales (13)	1958–1962 1979–1982			Increasing incidence of PUC* and NSAID use in elderly ♀	National register
Scotland (13)	1958–1962 1979–1982			Increasing incidence of PUC* and NSAID use in elderly ♀	National register
USA (45)	1974–1976 1984-1984	No rate per 100000 inhab	No rate per 100000 inhab	13% increase in perforations and 7% increase in bleedings after H2-rec blocker introduction	Cases operated
Poland (11)	1977–1996	No rate per 100000 inhab		Constant number/year, increasing % elderly women, increasing mean age	Cases operated
Hong-Kong (19)	1979–1985	14–18			Operating room logbooks
New South Wales (19)	1979–1985	3–4			Diagnosis reported to dept of heath
Finland (12,46)	1972–1987 1987–1999	4–5 5–7	3–4	Increasingly more ♀, increasing mean age	Cases operated, national register
Sweden (1)	1974–92	2–11		Significant decrease in incidence	Patients records
Denmark (20)	1974–1984	4–10	5–10	No significant difference before/after H2-receptor blockers	Cases operated
Finland (17)	1977–1989	2–8	3–9	No significant difference before/after H2-receptor blockers	Cases operated
Finland (15)	1979-85-00	3-6-4		No significant difference before/after H2-receptor blockers or PPI	Patients records
UK (10)	1989–99	♂ 10–11 ♀ 7-7	27–31 14–16		Admittance rates
UK (47)	1996–98	♂ 5 ♀ 4		Only duodenal perforations, increasing mean age in ♀	Patients records
Germany (23)	1989–90 1999-00		51 49	Patients older and more NSAID use in the later period	Prospective

*PUC = peptic ulcer complications