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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: Exp Neurol. 2009 Feb 3;217(1):46–54. doi: 10.1016/j.expneurol.2009.01.015

Fig. 3. Examples of direct transitions from Wake to REM sleep and wake-interrupted REM sleep.

Fig. 3

In this TG mouse, the DREM transition characteristically followed an extended episode of wakefulness, ending with a transition back to wakefulness and occurred during the dark period (ZT 23) (3a). In contrast, the REM-to-Wake transition in the WT mouse interrupted an extended bout of REM sleep and occurred during the light period (ZT 8 and ZT 10.5) (3b, c).