Table 3. Suggested frequency of monitoring during and after antiviral therapy.

Serum marker	On therapy	After therapy
HBV DNA	Every 12 weeks (every 24 weeks after one year)	Every 4 to12 weeks (every 24 to 48 weeks after one year)
HBeAg, anti-HBe	Every 24 weeks (If HBeAg positive)	Every 4 to 12 weeks (every 24 to 48 weeks after one year)
HBsAg	Every 24 to 48 weeks (If HBeAg negative)	Every 48 weeks
ALT	Every 12 weeks	Every 12 weeks
Liver biopsy	Not Needed	Individualized
Creatinine/Phosphate (ADV/TDF)	Every 12 weeks	Not needed
CBC (Interferon)	Every 4 weeks	Not Needed
TSH (Interferon)	Every 12 weeks	Not needed

Abbreviations: ADV, adefovir; TDF, tenofovir; CBC, complete blood count; TSH, thyroid stimulating hormone