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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: Exp Neurol. 2009 Feb 10;217(1):136–146. doi: 10.1016/j.expneurol.2009.01.023

Figure 4. Wild-type mice treated with PAR1 antagonist are protected from NMDA-induced damage.

Figure 4

A) Cresyl violet staining is shown for wild-type mouse striatal sections 24 hours after NMDA injection. B) Mean lesion volume induced by intrastriatal NMDA injection into wild-type mice pretreated with either vehicle or PAR1 antagonist delivered ICV (1 μl of PBS or 6 mM antagonist in PBS given over 3 minutes); * p<0.01 (ANOVA n=6 animals per condition). Lesion volumes from mice injected with phosphate-buffered saline (PBS) were undetectable (not shown). Error bars indicate SEM.