TABLE 5.

Regional Volumetric Data for the Study Subjects

Region	Preterm, Least Square Mean ± SE, cc3		Term, Least Square Mean ± SE, cc3		P
	8 y	12 y	8 y	12 y	Group	Time	Group × Time
Gray matter
Frontal
Left	116.80 ± 1.06	115.82 ± 1.06	116.86 ± 1.77	110.62 ± 1.77	.16	.004	.032
Right	117.69 ± 1.69	116.39 ± 1.15	115.99 ± 1.91	111.27 ± 1.91	.11	.008	.122
Temporal
Left	66.57 ± 0.91	65.40 ± 0.91	71.59 ± 1.52	61.32 ± 1.52	.77	<.001	<.001
Right	64.71 ± 0.77	63.90 ± 0.77	67.53 ± 1.28	60.19 ± 1.28	.73	<.001	<.001
Parietal
Left	80.69 ± 0.90	77.22 ± 0.90	81.18 ± 1.50	69.14 ± 1.50	.009	<.001	<.001
Right	81.50 ± 0.92	76.99 ± 0.92	80.23 ± 1.53	68.94 ± 1.53	.003	<.001	.004
Occipital
Left	37.07 ± 0.60	36.54 ± 0.60	39.85 ± 1.00	36.69 ± 1.00	.19	<.001	.015
Right	38.44 ± 0.65	36.61 ± 0.65	40.87 ± 1.09	37.90 ± 1.09	.13	<.001	.351
Deep gray
Left	20.27 ± 0.25	19.29 ± 0.54	23.20 ± 0.42	20.55 ± 0.42	<.001	<.001	.009
Right	19.34 ± 0.23	17.99 ± 0.23	21.92 ± 0.38	19.69 ± 0.38	<.001	<.001	.073
White matter
Frontal
Left	70.35 ± 0.97	76.99 ± 0.97	67.46 ± 1.62	82.03 ± 1.62	.55	<.001	<.001
Right	72.90 ± 1.10	79.13 ± 1.10	69.19 ± 1.83	83.70 ± 1.83	.83	<.001	<.001
Temporal
Left	32.26 ± 0.84	35.86 ± 0.84	31.86 ± 1.40	44.01 ± 1.40	.008	<.001	<.001
Right	31.12 ± 0.89	35.03 ± 0.89	30.70 ± 1.48	44.71 ± 1.48	.003	<.001	<.001
Parietal
Left	55.57 ± 0.92	62.89 ± 0.92	51.15 ± 1.53	68.99 ± 1.53	.58	<.001	<.001
Right	55.24 ± 0.84	61.47 ± 0.84	52.23 ± 1.39	67.23 ± 1.39	.31	<.001	<.001
Occipital
Left	25.46 ± 0.57	26.08 ± 0.57	23.76 ± 0.96	26.93 ± 0.96	.69	.003	.013
Right	22.94 ± 0.65	24.41 ± 0.65	22.32 ± 1.08	26.14 ± 1.08	.66	<.001	.032
Deep white
Left	18.60 ± 0.28	20.36 ± 0.28	17.91 ± 0.46	21.29 ± 0.46	.80	<.001	.015
Right	19.29 ± 0.25	21.35 ± 0.25	19.27 ± 0.42	22.26 ± 0.42	.33	<.001	.073