Skip to main content
. Author manuscript; available in PMC: 2009 May 10.
Published in final edited form as: Mol Carcinog. 2008 May;47(5):326–337. doi: 10.1002/mc.20389

Figure 6.

Figure 6

DLC-1 reduces NSCLC invasion in vitro. NCI-H23 cells stably-infected with the pBabe-puro vector encoding DLC-1 or DLC-1(R718E) were assessed for invasion through Matrigel. Cells were dissociated, resuspended in serum-free growth media containing 1% BSA, and incubated for 22 h at 37°C in a Matrigel invasion chamber; the lower well contained growth medium supplemented with 3% FCS. Non-invaders were removed, and the chambers were fixed and stained. (A) Invading cells were photographed under 10X magnification. (B) Quantification of invading cells. Data shown are the mean ± SD of triplicate wells and are representative of two independent experiments. *, significant at P ≤; 0.01 vs. vector.