TABLE 1.
Baseline characteristics of control and case subjects in the E3N-EPIC Study, France, 1995–1998
Characteristic | Controls (n = 702) | Cases (n = 363) | p value* |
---|---|---|---|
Mean age (years) at blood collection | 56.8 (6.3)† | 56.8 (6.3) | 0.31 |
Mean body mass index at blood collection ‡ | 24.1 (3.6) | 23.8 (3.7) | 0.14 |
Mean adult height (cm) | 160.4 (5.6) | 161.1 (6.0) | 0.05 |
Age (years) at menarche (%) | |||
<12 | 19.1 | 19.1 | 0.97 |
12–13 | 53.1 | 52.7 | |
≥14 | 27.7 | 28.2 | |
Combined age at first birth and parity (%) | |||
Nulliparous | 12.8 | 16.0 | 0.03 |
First birth before age 30 years, 1–2 children | 46.7 | 46.3 | |
First birth before age 30 years, ≥3 children | 30.6 | 24.0 | |
First birth after age 30 years | 9.8 | 13.8 | |
Age (years) at menopause (%) | |||
Premenopausal | 24.6 | 23.1 | 0.43 |
≤45 | 7.6 | 8.3 | |
46–54 | 61.1 | 59.8 | |
>54 | 6.7 | 8.8 | |
Ever use of menopausal hormones (%) | 57.8 | 63.6 | 0.02 |
Years of education (%) | |||
<12 | 11.4 | 11.1 | 0.05 |
12–14 | 46.6 | 48.3 | |
15–16 | 22.9 | 16.5 | |
≥17 | 19.1 | 24.2 | |
History of benign breast disease (%) | 31.8 | 41.1 | 0.002 |
Familial history of breast cancer (%) | 14.4 | 21.2 | 0.007 |
Smoking status at blood collection (%) | |||
Nonsmoker (never or former smoker) | 93.5 | 92.3 | |
Smoker | 6.6 | 7.7 | 0.46 |
Baseline characteristics of cases and controls were compared using Student’s t test for continuous variables and the chi-squared test for categorical variables.
Numbers in parentheses, standard deviation.
Weight (kg)/height (m)2.