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. Author manuscript; available in PMC: 2010 Feb 7.
Published in final edited form as: J Mol Biol. 2008 Dec 11;385(5):1643–1654. doi: 10.1016/j.jmb.2008.11.058

Table 3.

GTP Analog: GTP-Bodipy competition analysis with DEN MTase

GTP analog Ki Standard Error Fold Affinity Reduction Purine Ring Structure
GTP 40nM 10nM 0 graphic file with name nihms100608t1.jpg
GDP 100nM 30nM 3
GMP 950nM 70nM 29
Guanosine 260μM 8uM 6400
dGTP 610nM 70nM 15
ddGTP 770nM 70nM 19
ATP 350uM 39uM 8750 graphic file with name nihms100608t2.jpg
ITP 120nM 30nM 3 graphic file with name nihms100608t3.jpg
XTP 480nM 110nM 12 graphic file with name nihms100608t4.jpg
6-methylthio GTP 230nM 90nM 6 graphic file with name nihms100608t5.jpg
7meGpppG 100nM 20nM 2.6 graphic file with name nihms100608t6.jpg
7meGpppA 170nM 20nM 4.1