Table 4.
Change in YMRS Scores from Baseline to End Point (N = 33)
| |
Baseline |
End point |
|
|
|
||||
|---|---|---|---|---|---|---|---|---|---|
| YMRS items | Mean | SD | % of total score | Mean | SD | % of total score | df | Test Value | p* |
| Total score | 23.7 | 3.53 | 15.4 | 6.15 | 32 | 8.3 | <.001 | ||
| ADHD items | 8.32 | 1.65 | 35% | 6.49 | 2.74 | 42% | 32 | 3.8 | <.001 |
| ODD items | 8.24 | 1.47 | 35% | 4.39 | 2.45 | 29% | 32 | 9.0 | <.001 |
| Mania specific items | 6.48 | 1.45 | 27% | 4.27 | 2.09 | 28% | 32 | 5.8 | <.001 |
Attention-deficit/hyperactivity disorder items are increased motor activity (#2), speech (#6), and language (#7).
Oppositional defiant disorder items are irritability (#5) and disruptive aggression behaviors (#9).
Mania-specific items are elevated mood (#1), sexual interest (#3), sleep (#4), and content (#8).
*
p set at 0.0125 to correct for multiple comparisons.
YMRS = Young Mania Rating Scale; SD = standard deviation; ADHD = attention-deficit/hyperactivity disorder; ODD = oppositional defiant disorder.