. Author manuscript; available in PMC: 2010 Mar 1.

Published in final edited form as: J Hepatol. 2008 Dec 29;50(3):538–547. doi: 10.1016/j.jhep.2008.10.028

Table 1.

Indices of hepatic inflammation & liver cell injury

Group	Week 2	Week 4	Week 8	Week 10	Specific Liver Disease Criteria
Dextrose fed rats	0 (7)	0 (6)	0 (7)	0 (6)	Necroinflammatory Histology score
Alcohol fed rats	0 (11)	0 (12)	2^*(±0.2) (10)	4^*(±0.5 ) (6)	Necroinflammatory Histology score
Dextrose fed rats	0.16 (±0.2)	0.13 (±0.2)	0.16 (±0.2)	0.13 (±0.02)	Liver MPO (U/mg tissue)
Alcohol fed rats	0.15 (± 0.2)	0.26 (± 0.05)	0.58^* (± .07)	2.37^* (± 0.3)	Liver MPO (U/mg tissue)
Dextrose fed rats	65.27 (± 7)	65.27 (± 7)	65.27 (± 7)	65.27 (± 7)	Serum ALT (U/dl)
Alcohol fed rats	90.74^*(± 10)	79.29^* (± 8)	100.84^* (± 11)	90.37^* (± 10)	Serum ALT (U/dl)
Dextrose fed rats	82.38 (± 9)	82.38 (± 9)	82.38 (± 9)	82.38 (± 9)	Serum AP (U/dl)
Alcohol fed rats	90.75 (±10)	110.83 (±12)	264.39^* (± 27)	220.47^* (± 21)	Serum AP (U/dl)

mean ± S.E.;

p ≤ 0.05 Alcohol fed rats vs. Dextrose fed rats; number in () represents number of rats in each group