Table 2.
Damage score, changes in colonic weight, changes in body weight and incidence of adhesions and diarrhoea of colitic rats with relapse induced by TNBS.
| Days of treatment | Damage score(a) (0–10) | Colonic weight(b) (mg/cm) | Body weight change (%) | Adhesions (%) | Diarrhoea (%) |
|---|---|---|---|---|---|
| 0 | 0 (0–0) | 67.2 ± 4.05 | 4.90 ± 0.50 | 0 | 0 |
| 2 | 7 (6–7.5) | 129.0 ± 9.72 | −7.20 ± 1.29 | 60 | 40 |
| 4 | 8 (6.5–9.5) | 157.0 ± 17.35 | −10.50 ± 0.52 | 80 | 100 |
| 6 | 7 (6–8) | 196.8 ± 40.45 | −3.56 ± 1.52 | 100 | 100 |
| 8 | 6 (5–7) | 130.2 ± 9.38 | 15.98 ± 2.67 | 60 | 80 |
| 10 | 7 (3.5–8) | 302.3 ± 63.78 | 24.02 ± 1.26 | 40 | 80 |
| 12 | 5 (1–5) | 159.8 ± 16.09 | 23.78 ± 1.58 | 20 | 40 |
| 14 | 1 (1-1) | 129.4 ± 6.01 | 26.48 ± 0.82 | 0 | 80 |
| 16 | 6 (6–6.5) | 159.9 ± 18.21 | 10.52 ± 0.85 | 20 | 100 |
| 18 | 7 (6–8) | 172.5 ± 17.37 | 14.68 ± 1.68 | 20 | 80 |
| 20 | 6 (5–6) | 147.2 ± 9.59 | 24.95 ± 1.51 | 20 | 100 |
| 22 | 5.5 (5–6.5) | 195.4 ± 17.77 | 29.12 ± 1.28 | 25 | 75 |
| 24 | 5 (5–6) | 149.5 ± 15.01 | 30.02 ± 1.96 | 0 | 75 |
| 26 | 3 (2-2) | 130.8 ± 4.97 | 35.85 ± 1.91 | 0 | 25 |
| 28 | 2 (2–3) | 142.4 ± 3.76 | 50.02 ± 2.02 | 0 | 0 |
| 32 | 1 (1–4) | 116.7 ± 6.89 | 51.58 ± 2.94 | 0 | 0 |
| 36 | 1 (0–1) | 123.6 ± 5.89 | 56.44 ± 2.19 | 0 | 0 |
| 40 | 1 (0–1) | 128.8 ± 3.23 | 62.85 ± 2.55 | 0 | 0 |
(a)Score data are expressed as median and interquartil interval. (b)Body weight changes is expressed as percentage change from the start of the experiment (N = 6).