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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Eur J Pharm Biopharm. 2008 Oct 17;71(3):519–528. doi: 10.1016/j.ejpb.2008.09.022

Table 2.

Common hydrogels used in the pharmaceutical field for the preparation of controlled drug delivery systems [65]

Hydrogel polymer Type of hydrogel

Poly(glycolic acid) (PGA) Biodegradable Hydrogels
Poly(lactic acid) (PLA)
PLA-PGA
PLA-PEG
Chitosan
Dextran
Dextran-PEG
Polycyanoacrylates
Fumaric acid-PEG

Non-Biodegradable Hydrogels

Poly(hydroxyethyl methacrylate) (PHEMA) Neutral
Poly(vinyl alcohol) (PVA)
Poly(N-vinyl pyrrolidone) (PNVP)
Poly(ethylene-co-vinyl acetate) (PEVAc)

Poly(acrylamide) (PAAm) pH-Responsive
Poly(acrylic acid) (PAA)
Poly(methacrylic acid) (PMAA)
Poly(diethylaminoetyl methacrylate) (PDEAEMA)
Poly(dimethylaminoethyl methacrylate) (PDMAEMA)

Poly(methacrylic acid-grafted-poly(ethylene glycol) (P(MAA-g-EG)) Complexing hydrogels
Poly(acrylic acid-grafted-poly(ethylene glycol) (P(AA-g-EG))

Poly(N-isopropyl acrylamide) (PNIPAAm) Temperature-sensitive

PNIPAAm/PAA pH/Temperature-sensitive
PNIPAAm/PMAA